Smooth g Delete data points
Deletes all data points within a rectangle you just drew.

g Discard (shift-Del)
Throws away the data points. The total
number of data points in your plot will decrease as a result.

g Interpolate (ctrl-Del)
Does not throw away the unwanted data
points, but puts them "into place". Spectrum Viewer will draw a line
between the surrounding valid data points and place the offending data points on
that line. The X value of the data point will be left alone, the Y value is calculated
so that the data point is placed on the line.

For data sets with a lot of spikes it is better to choose the delete large spikes command. See also this tutorial.